FOXI1 Antikörper (AA 101-200)

Produktnummer ABIN1714165

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch FOXI1 in ELISA, IHC (p), IF (cc), IF (p), IHC (fro) und ICC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FOXI1 Antikörper (AA 101-200) (ABIN1714165)

Target: FOXI1 (Forkhead Box I1 (FOXI1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXI1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Produktdetails anti-FOXI1 Antikörper

Bindungsspezifität: AA 101-200

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FOXI1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu FOXI1

Target: FOXI1 (Forkhead Box I1 (FOXI1))

Andere Bezeichnung: FOXI1

Hintergrund:

Synonyms: FKH10, FKHL10, Forkhead Drosophila like 10, Forkhead box I1, Forkhead box protein I1, Forkhead like 10, Forkhead related activator 6, Forkhead related transcription factor 6, Forkhead-related protein FKHL10, FREAC 6, FREAC6, Hepatocyte nuclear factor 3 forkhead homolog 3, HFH 3, HFH3, HNF 3/fork head homolog 3, HNF-3 fork-head homolog 3, Human HNF-3 fork-head homolog-3 HFH-3 mRNA complete cds, MGC34197, FOXI1_HUMAN.

Background: FOXI1 is a member of the FOX family of transcription factors. The FOX family is a large group of proteins (consisting of at least 43 members) that share a common DNA binding domain termed winged-helix or forkhead domain. FOX transcription factors play important roles in development, differentiation, aging and hormone responsiveness. Localizing to the nucleus, FOXI1 functions as a transcription factor. Mice with mutated forms of FOXI1 show defects in ear development, implying that FOXI1 plays a significant role in the developmental pathway of ears and, in particular, the cochlea and vestibulum. FOXI1 is an upstream transcription regulator of Pendrin (a protein associated with deafness), suggesting a role for FOXI1 in the pathogenesis of Pendred syndrome (PS), a condition of nonsyndromic hearing loss and enlarged vestibular aqueduct (EVA).

Gen-ID: 2299